Entertainment

Grey’s Anatomy Season 22 Episode 3: Release Date, Time, Where to Watch, and What to Expect

By

Anshul Kamboj

The long-running medical drama Grey’s Anatomy continues to keep viewers hooked with its blend of emotional storytelling, complex characters, and intense surgical moments. The upcoming episode, Season 22, Episode 3, titled “Between Two Lungs,” is set to deliver another high-stakes medical case that tests the limits of the doctors at Grey Sloan Memorial Hospital.

Here’s everything you need to know about the release date, time, where to watch, and what to expect from the next chapter in the hit ABC series.

Grey’s Anatomy Season 22 Episode 3 Release Date and Time

Grey’s Anatomy Season 22 Episode 3 will air on Thursday, October 23, 2025, at 10 p.m. ET / 7 p.m. PT on ABC. The episode will also be available for next-day streaming on Hulu, allowing fans to catch up on the drama whenever they want.

U.S. Release Schedule

Time ZoneRelease DateRelease Time
Eastern Time (ET)October 23, 202510:00 PM
Pacific Time (PT)October 23, 20257:00 PM

The show continues its Thursday night slot as part of ABC’s “TGIT” (Thank God It’s Thursday) lineup, alongside other fan-favorite dramas.

Where to Watch Grey’s Anatomy Season 22 Episode 3

Grey's Anatomy

Fans can watch Grey’s Anatomy Season 22 Episode 3 live on ABC or stream it the next day on Hulu.

  • Watch Live: Tune in on ABC Network via cable TV or live TV streaming services like Hulu + Live TV, YouTube TV, or FuboTV.
  • Stream On-Demand: The episode will be available to stream on Hulu beginning Friday, October 24, 2025, with all previous episodes from Season 22 also available on the platform.

What Happened So Far in Season 22

The new season has kicked off with emotional turbulence and fresh challenges for the staff at Grey Sloan Memorial Hospital. Following the dramatic events of last season, the surgical team is striving to find stability amid professional rivalries and personal conflicts.

In the opening episodes, we’ve seen Bailey (Chandra Wilson) balancing her return to hands-on surgery with new teaching responsibilities, while Meredith Grey’s absence continues to reshape the hospital’s leadership structure. Meanwhile, Dr. Amelia Shepherd (Caterina Scorsone) and Dr. Winston Ndugu (Anthony Hill) have been clashing over medical ethics, and Dr. Levi Schmitt (Jake Borelli) faces the challenge of mentoring a new batch of interns.

The hospital’s residents are once again at the center of chaos — navigating high-pressure surgeries, personal heartbreak, and ethical dilemmas that test their resilience.

What to Expect from Grey’s Anatomy Season 22 Episode 3

Episode 3, titled “Between Two Lungs,” will reportedly center on a high-risk lung transplant that puts both the patient and the surgical team under immense pressure. Expect tense operating room scenes and emotional stakes as the doctors race against time to perform the life-saving procedure.

Grey's Anatomy' Season 22 Release Schedule

Meanwhile, Dr. Miranda Bailey will handle a trauma patient whose condition is dangerously unstable. Her decision-making will be pushed to the limit as she balances her instincts with the demands of modern medicine.

As usual, viewers can anticipate a mix of heart-pounding medical drama and emotional character development. The episode is expected to delve deeper into themes of sacrifice, teamwork, and personal loss, which have long defined the series.

The Cast of Grey’s Anatomy Season 22

Season 22 features a strong returning ensemble, alongside several new faces who are reshaping the hospital’s dynamic.

Main Cast:

  • Chandra Wilson as Dr. Miranda Bailey
  • James Pickens Jr. as Dr. Richard Webber
  • Kevin McKidd as Dr. Owen Hunt
  • Caterina Scorsone as Dr. Amelia Shepherd
  • Camilla Luddington as Dr. Jo Wilson
  • Jake Borelli as Dr. Levi Schmitt
  • Kim Raver as Dr. Teddy Altman
  • Anthony Hill as Dr. Winston Ndugu
  • Adelaide Kane as Dr. Jules Millin

Though Ellen Pompeo (Meredith Grey) has stepped away from her full-time role, her presence continues to shape the storylines and emotional undertones of the show.

How Many Episodes Are in Grey’s Anatomy Season 22?

While ABC has not confirmed the total episode count, the season is expected to feature 18–20 episodes, similar to previous seasons. New episodes air weekly every Thursday night, continuing the show’s long-standing tradition of delivering heartfelt storytelling and high-stakes drama.

FAQs

1. When will Grey’s Anatomy Season 22 Episode 3 be released?
Episode 3 premieres on Thursday, October 23, 2025, at 10 p.m. ET / 7 p.m. PT on ABC.

2. Where can I watch the new episode?
You can watch it live on ABC or stream it the next day on Hulu.

3. What is the title of Episode 3?
Episode 3 is titled “Between Two Lungs.”

4. How many episodes are there in Season 22?
The season is expected to include 18–20 episodes airing weekly through early 2026.

5. What is Grey’s Anatomy about?
The series follows the personal and professional lives of surgeons at Grey Sloan Memorial Hospital, exploring how they navigate the pressures of medicine, love, and loss.

Final Thoughts

With over two decades of captivating storytelling, Grey’s Anatomy continues to prove its staying power. Episode 3, “Between Two Lungs,” is expected to bring a perfect mix of emotional depth and intense medical drama, reaffirming why this series remains one of television’s most enduring hits.

Don’t miss Grey’s Anatomy Season 22 Episode 3 when it airs Thursday, October 23, 2025, at 10 p.m. ET on ABC, and stream it the next day on Hulu.

What do you think will happen during the high-risk transplant? Share your predictions in the comments and join the discussion on TrendingNewsBuzz.com.