The long-running medical drama Grey’s Anatomy is returning for Season 22, and fans can expect even more drama, explosive moments, and unexpected twists. After the shocking cliffhanger in Season 21, where the hospital faced a massive explosion, Season 22 promises to continue the high-stakes action. Here’s everything you need to know about Season 22 of Grey’s Anatomy, including its premiere date, cast updates, and what’s next for the beloved characters.
When Does Grey’s Anatomy Season 22 Premiere?
Grey’s Anatomy Season 22 will premiere on Thursday, October 9, 2025, at 10:00 p.m. ET/PT on ABC. The show will be airing in a new timeslot, following Shifting Gears and The Golden Bachelor. The premiere will set the stage for what promises to be another unforgettable season filled with hospital drama, love, and loss.
What Time Does Grey’s Anatomy Come On?
The Season 22 premiere airs at 10:00 p.m. ET/PT on ABC. Fans can tune in weekly to catch the latest episode at the same time. For those who prefer to stream, episodes will be available on Hulu the following day.
How to Stream Grey’s Anatomy Season 22
For those who miss the live airing, Grey’s Anatomy will be available to stream on Hulu the day after each episode airs on ABC. Whether you catch it live or stream it at your convenience, you won’t miss a moment of the action.
Who’s Returning for Grey’s Anatomy Season 22?
The core cast of Grey’s Anatomy is back for another season, including:
- Ellen Pompeo as Meredith Grey
- Chandra Wilson as Miranda Bailey
- James Pickens Jr. as Richard Webber
- Kevin McKidd as Owen Hunt
- Kim Raver as Teddy Altman
- Caterina Scorsone as Amelia Shepherd
- Camilla Luddington as Jo Wilson
- Jason George as Ben Warren
- Chris Carmack as Atticus “Link” Lincoln
- Anthony Hill as Winston Ndugu
- Alexis Floyd as Simone Griffith
- Harry Shum Jr. as Benson “Blue” Kwan
- Adelaide Kane as Jules Millin
- Niko Terho as Lucas Adams
Fans can also expect Ellen Pompeo to make increased appearances, following her reduced role in Season 19. Pompeo continues to be an integral part of the series, despite her shift to a more occasional role.
Will Link Be Returning for Grey’s Anatomy Season 22?
Chris Carmack, who plays Link, was left in a dangerous situation at the end of Season 21, with the explosion at Grey Sloan. The fate of Link was uncertain, leading many to question if he survived. Carmack has been tight-lipped about his character’s status, but fans are hoping he will return in full force for Season 22, albeit potentially dealing with severe injuries from the explosion.
New Faces: Luke Tennie Joins the Cast
In exciting news, Luke Tennie of Shrinking fame will join the Season 22 cast as Dominic, a new teacher at Grey Sloan Memorial Hospital. Tennie’s character will make his debut in the Season 22 premiere, adding a fresh dynamic to the team. His character’s arrival promises to shake things up, and it will be interesting to see how Dominic fits into the established team of doctors and surgeons.
What Happened at the End of Grey’s Anatomy Season 21?
The Season 21 finale of Grey’s Anatomy was packed with tension. The doctors at Grey Sloan were caught in a hostage situation when a mother, desperate to save her child’s life, threatened to blow up the hospital. In a nail-biting conclusion, the explosion rocked the upper floor of Grey Sloan, leaving Link and others in peril.
While the drama played out in the finale, there were no major cliffhangers regarding the core relationships, and the season ended with Simone and Lucas reconciling and Jules and Winston facing their own romantic tension.
What to Expect in Grey’s Anatomy Season 22
Fans can expect plenty of relationship drama, heart-wrenching moments, and medical crises in Season 22. The show will continue to explore the complicated dynamics between the doctors, as well as new storylines involving Dominic. Some key themes for the upcoming season include:
- Link’s recovery and the aftermath of the explosion.
- Simone and Lucas’ evolving relationship.
- Winston and Jules navigating the tension in their professional and personal lives.
- Meredith Grey’s continuing journey as a mother, doctor, and mentor.
Ellen Pompeo’s return as Meredith will undoubtedly provide pivotal moments as she continues to navigate her evolving relationship with the hospital and the people who have shaped her career.
What Will Happen with the Cast Departure?
One of the key points to keep an eye on is the potential cast departure of Ellen Pompeo. Though she will make several appearances in Season 22, her reduced role in Season 19 raised questions about the future of Meredith Grey on the show. Fans will likely see Meredith transition into a more limited role, while other characters, such as Amelia and Teddy, take center stage in their own storylines.
Trailer for Grey’s Anatomy Season 22
Ahead of the Season 22 premiere, ABC has released an official trailer for the upcoming season, giving viewers a first look at what’s in store. The teaser highlights the intense medical drama, personal relationship struggles, and the return of Link and Meredith in their respective arcs. Fans can expect to see the fallout from the explosion, new challenges for the doctors at Grey Sloan, and plenty of emotional moments that will have everyone talking.
The trailer promises an exciting new season, with new conflicts, returning relationships, and a fresh team dynamic that will keep fans on the edge of their seats.
FAQs About Grey’s Anatomy Season 22
1. When does Grey’s Anatomy Season 22 premiere?
Grey’s Anatomy Season 22 premieres on Thursday, October 9, 2025, at 10:00 p.m. ET/PT on ABC.
2. How many episodes are in Season 22?
Season 22 is expected to feature 18 episodes, the same as the previous season.
3. Who will be in the cast for Season 22?
The main cast, including Ellen Pompeo, Chandra Wilson, Kevin McKidd, and Kim Raver, will return, with Luke Tennie joining as a new teacher named Dominic.
4. What happened in the Season 21 finale?
The Season 21 finale featured a hostage situation and a massive explosion that left Link and others in danger, setting up the events of Season 22.
5. Where can I watch Grey’s Anatomy Season 22?
Grey’s Anatomy airs on ABC and streams on Hulu the next day.
Final Thoughts
With Grey’s Anatomy Season 22, fans can expect more drama, excitement, and emotional moments as the doctors of Grey Sloan Memorial Hospital face new challenges, both personal and professional. With the return of Meredith, the introduction of Luke Tennie’s character, and fresh storylines on the horizon, it looks like Season 22 will be another unforgettable chapter in the series.
What are you most excited about for Season 22? Share your thoughts in the comments and join the conversation on TrendingNewsBuzz.com!
